甲(jia)(jia)(jia)基(ji)丙(bing)(bing)(bing)(bing)(bing)烯(xi)(xi)酸(suan)的工业(ye)生产(chan)(chan)方(fang)法(fa)(fa)主(zhu)要(yao)有(you)两(liang)种，即丙(bing)(bing)(bing)(bing)(bing)酮(tong)(tong)氰(qing)(qing)醇(chun)法(fa)(fa)是异(yi)(yi)丁(ding)(ding)(ding)烯(xi)(xi)（叔丁(ding)(ding)(ding)醇(chun)）氧化(hua)(hua)(hua)(hua)(hua)法(fa)(fa)。1.丙(bing)(bing)(bing)(bing)(bing)酮(tong)(tong)氰(qing)(qing)醇(chun)法(fa)(fa)丙(bing)(bing)(bing)(bing)(bing)酮(tong)(tong)和(he)氢氰(qing)(qing)酸(suan)在(zai)碱催化(hua)(hua)(hua)(hua)(hua)剂存在(zai)下，反应(ying)生成(cheng)丙(bing)(bing)(bing)(bing)(bing)酮(tong)(tong)氰(qing)(qing)醇(chun)，再与浓硫(liu)(liu)酸(suan)反应(ying)生成(cheng)甲(jia)(jia)(jia)基(ji)丙(bing)(bing)(bing)(bing)(bing)烯(xi)(xi)酰胺硫(liu)(liu)酸(suan)盐，然(ran)后经(jing)水解即可(ke)生成(cheng)甲(jia)(jia)(jia)基(ji)丙(bing)(bing)(bing)(bing)(bing)烯(xi)(xi)酸(suan)。生产(chan)(chan)中(zhong)要(yao)求(qiu)丙(bing)(bing)(bing)(bing)(bing)酮(tong)(tong)氰(qing)(qing)醇(chun)和(he)硫(liu)(liu)酸(suan)中(zhong)不含水分，否则会产(chan)(chan)生丙(bing)(bing)(bing)(bing)(bing)酮(tong)(tong)或α-羟基(ji)异(yi)(yi)丁(ding)(ding)(ding)酸(suan)甲(jia)(jia)(jia)酯(zhi)留(liu)在(zai)产(chan)(chan)品(pin)(pin)中(zhong)，影响产(chan)(chan)品(pin)(pin)质(zhi)量。用(yong)丙(bing)(bing)(bing)(bing)(bing)酮(tong)(tong)氰(qing)(qing)醇(chun)法(fa)(fa)生产(chan)(chan)甲(jia)(jia)(jia)基(ji)丙(bing)(bing)(bing)(bing)(bing)烯(xi)(xi)酸(suan)，每吨(dun)产(chan)(chan)品(pin)(pin)消耗(hao)氰(qing)(qing)化(hua)(hua)(hua)(hua)(hua)钠（>87）898kg、丙(bing)(bing)(bing)(bing)(bing)酮(tong)(tong)（98.5）1100kg、硫(liu)(liu)酸(suan)（发烟(yan)）4080kg。2.异(yi)(yi)丁(ding)(ding)(ding)烯(xi)(xi)（叔丁(ding)(ding)(ding)醇(chun)）氧化(hua)(hua)(hua)(hua)(hua)法(fa)(fa)异(yi)(yi)丁(ding)(ding)(ding)烯(xi)(xi)经(jing)两(liang)步氧化(hua)(hua)(hua)(hua)(hua)，第(di)一步生成(cheng)甲(jia)(jia)(jia)基(ji)丙(bing)(bing)(bing)(bing)(bing)烯(xi)(xi)醛(quan)，第(di)二步生成(cheng)甲(jia)(jia)(jia)基(ji)丙(bing)(bing)(bing)(bing)(bing)烯(xi)(xi)酸(suan)，然(ran)后经(jing)精馏得(de)到合格产(chan)(chan)品(pin)(pin)。3.甲(jia)(jia)(jia)基(ji)丙(bing)(bing)(bing)(bing)(bing)烯(xi)(xi)腈(jing)水解法(fa)(fa)以(yi)异(yi)(yi)丁(ding)(ding)(ding)烯(xi)(xi)为原(yuan)料(liao)，经(jing)氨(an)氧、水解而得(de)。4.异(yi)(yi)丁(ding)(ding)(ding)烷氧化(hua)(hua)(hua)(hua)(hua)法(fa)(fa)经(jing)氧化(hua)(hua)(hua)(hua)(hua)制得(de)甲(jia)(jia)(jia)基(ji)丙(bing)(bing)(bing)(bing)(bing)烯(xi)(xi)醛(quan)，再经(jing)氧化(hua)(hua)(hua)(hua)(hua)而得(de)。