甲(jia)基(ji)丙(bing)(bing)(bing)烯(xi)(xi)酸(suan)(suan)的工业生(sheng)(sheng)产(chan)(chan)方法(fa)(fa)(fa)(fa)(fa)(fa)主(zhu)要有两种，即(ji)丙(bing)(bing)(bing)酮(tong)(tong)氰(qing)醇(chun)(chun)法(fa)(fa)(fa)(fa)(fa)(fa)是(shi)异(yi)(yi)丁(ding)(ding)(ding)烯(xi)(xi)（叔(shu)丁(ding)(ding)(ding)醇(chun)(chun)）氧(yang)(yang)化(hua)(hua)(hua)(hua)法(fa)(fa)(fa)(fa)(fa)(fa)。1.丙(bing)(bing)(bing)酮(tong)(tong)氰(qing)醇(chun)(chun)法(fa)(fa)(fa)(fa)(fa)(fa)丙(bing)(bing)(bing)酮(tong)(tong)和氢氰(qing)酸(suan)(suan)在碱催化(hua)(hua)(hua)(hua)剂存在下，反应生(sheng)(sheng)成丙(bing)(bing)(bing)酮(tong)(tong)氰(qing)醇(chun)(chun)，再与浓硫(liu)酸(suan)(suan)反应生(sheng)(sheng)成甲(jia)基(ji)丙(bing)(bing)(bing)烯(xi)(xi)酰胺硫(liu)酸(suan)(suan)盐，然后经(jing)水(shui)解即(ji)可生(sheng)(sheng)成甲(jia)基(ji)丙(bing)(bing)(bing)烯(xi)(xi)酸(suan)(suan)。生(sheng)(sheng)产(chan)(chan)中(zhong)要求丙(bing)(bing)(bing)酮(tong)(tong)氰(qing)醇(chun)(chun)和硫(liu)酸(suan)(suan)中(zhong)不含水(shui)分，否则(ze)会(hui)产(chan)(chan)生(sheng)(sheng)丙(bing)(bing)(bing)酮(tong)(tong)或α-羟基(ji)异(yi)(yi)丁(ding)(ding)(ding)酸(suan)(suan)甲(jia)酯留在产(chan)(chan)品(pin)中(zhong)，影响(xiang)产(chan)(chan)品(pin)质量。用丙(bing)(bing)(bing)酮(tong)(tong)氰(qing)醇(chun)(chun)法(fa)(fa)(fa)(fa)(fa)(fa)生(sheng)(sheng)产(chan)(chan)甲(jia)基(ji)丙(bing)(bing)(bing)烯(xi)(xi)酸(suan)(suan)，每吨产(chan)(chan)品(pin)消耗氰(qing)化(hua)(hua)(hua)(hua)钠（>87）898kg、丙(bing)(bing)(bing)酮(tong)(tong)（98.5）1100kg、硫(liu)酸(suan)(suan)（发烟）4080kg。2.异(yi)(yi)丁(ding)(ding)(ding)烯(xi)(xi)（叔(shu)丁(ding)(ding)(ding)醇(chun)(chun)）氧(yang)(yang)化(hua)(hua)(hua)(hua)法(fa)(fa)(fa)(fa)(fa)(fa)异(yi)(yi)丁(ding)(ding)(ding)烯(xi)(xi)经(jing)两步(bu)氧(yang)(yang)化(hua)(hua)(hua)(hua)，第(di)一步(bu)生(sheng)(sheng)成甲(jia)基(ji)丙(bing)(bing)(bing)烯(xi)(xi)醛(quan)，第(di)二步(bu)生(sheng)(sheng)成甲(jia)基(ji)丙(bing)(bing)(bing)烯(xi)(xi)酸(suan)(suan)，然后经(jing)精馏得到合格产(chan)(chan)品(pin)。3.甲(jia)基(ji)丙(bing)(bing)(bing)烯(xi)(xi)腈水(shui)解法(fa)(fa)(fa)(fa)(fa)(fa)以异(yi)(yi)丁(ding)(ding)(ding)烯(xi)(xi)为原(yuan)料(liao)，经(jing)氨氧(yang)(yang)、水(shui)解而得。4.异(yi)(yi)丁(ding)(ding)(ding)烷氧(yang)(yang)化(hua)(hua)(hua)(hua)法(fa)(fa)(fa)(fa)(fa)(fa)经(jing)氧(yang)(yang)化(hua)(hua)(hua)(hua)制得甲(jia)基(ji)丙(bing)(bing)(bing)烯(xi)(xi)醛(quan)，再经(jing)氧(yang)(yang)化(hua)(hua)(hua)(hua)而得。